disease association

RichR

It provides a list of genes associated to diseases (g2d$clean and g2d$complete) based on the following 4 publications (GS2D, Fontaine (2016) doi:10.18547/gcb.2016.vol2.iss1.e33, DisGeNET, Pinero (2016) doi:10.1093/nar/gkw943 Berto2016, Berto (2016) doi:10.3389/fgene.2016.00031 and PsyGeNET, Sacristan (2015) doi:10.1093/bioinformatics/btv301). Those lists were combined and manually curated to have matching disease names. When provided a list of gene names, it calculates the disease enrichment of the gene set. The enrichment is calculated using proportion test and Fisher’s exact test. Adjusted fdr p-values are returned alongside with p-values combined using the Fisher’s method.